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To further interrogate the underlying dynamics of the Cagri-AMY 3 R complex, relative to rAmy-AMY 3 R complex, we performed molecular dynamics (MD) simulations of Cagri:AMY 3 R:Gα s and rAmy:AMY 3 R:Gα s (each system in triplicate, for a total of 6 μs)

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