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Our results indicated that neither GHK nor GHK-Cu showed cytotoxic activity at the range of concentrations tested while CuCl 2 and Cu(OAc) 2 showed substantial cytotoxicity to the HaCaT cells at the highest concentration assayed, i.e., at 5800 μM, after 30 mins treatment

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T2D accounts for 96% of diabetes and is one of the important noncommunicable chronic diseases that seriously threaten human health, without totally clear cognition on pathogenesis