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Redox dysregulation is also linked to protein misfolding by the production of aberrant, non-native disulfide bonds in both mutant SOD1 and TDP-43, which leads to the formation of inclusions and induces toxicity

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This multidisciplinary approach enables researchers to uncover the complex mechanisms underpinning autism, such as the role of specific genes like SHANK3 or microexons in CPEB4, and how these influence brain development and function